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DeepSeek in Healthcare: A Survey of Capabilities, Risks, and Clinical Applications of Open-Source Large Language Models
Ye, Jiancheng, Bronstein, Sophie, Hai, Jiarui, Hashish, Malak Abu
ABSTRACT DeepSeek - R1 is a cutting - edge open - source large language model (LLM) developed by DeepSeek, showcasing advanced reasoning capabilities through a hybrid architecture that integrates m ixture of e xperts (MoE), chain of thought (CoT) reasoning, and reinforcement learning. Released under the per missive MIT license, DeepSeek - R1 offers a transparent and cost - effective alternative to proprietary models like GPT - 4o and Claude - 3 Opus; i t excels in structured problem - solving domains such as mathematics, healthcare diagnostics, code generation, and phar maceutical research. Its architecture enables efficient inference while preserving reasoning depth, making it suitable for deployment in resource - constrained settings. However, DeepSeek - R1 also exhibits increased vulnerability to bias, misinformat ion, adversarial manipulation, and safety failures - especially in multilingual and ethically sensitive contexts. Th is survey highlights the model's strengths, including interpretability, scalability, and adaptability, alongside its limitations in general language fluency and safety alignment. Future research priorities include improving bias mitigation, natural language compreh ension, domain - specific validation, and regulatory compliance. Overall, DeepSeek - R1 represents a major advance in open, scalable AI, underscoring the need for collaborative governance to ensure responsible and equitable deployment. INTRODUCTION T he rise of AI and generative models in health and technology Artificial Intelligence (AI) has undergone transformative growth in recent years, profoundly reshaping numerous fields including language processing, automation, and complex decision - making. At its core, AI refers to the simulation of human intelligence by machines, enabling them to perform tasks such as speech recognition, natural lang uage understanding, visual perception, and predictive analytics. One of the recent remarkable advancements in the Generative AI domain is the emergence of DeepSeek - R1, a large language model (LLM) developed by the Chinese company DeepSeek. In benchmarking evaluations, it has demonstrated results competitive with, and in some domains superior to, models like OpenAI's GPT - 4o and GPT - o1 [4] . This has positioned DeepSeek - R1 as a notable advancement not only in LLM capability but also in the global AI development race. DeepSeek - R1: a paradigm shift in LLM development What sets DeepSeek - R1 apart from conventional LLMs is its novel training architecture. This hybrid approach mimics certain aspects of human learning, allowing the model to refine its behavior over time and adapt to mo re complex reasoning tasks.
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MedPAIR: Measuring Physicians and AI Relevance Alignment in Medical Question Answering
Hao, Yuexing, Alhamoud, Kumail, Jeong, Hyewon, Zhang, Haoran, Puri, Isha, Torr, Philip, Schaekermann, Mike, Stern, Ariel D., Ghassemi, Marzyeh
Large Language Models (LLMs) have demonstrated remarkable performance on various medical question-answering (QA) benchmarks, including standardized medical exams. However, correct answers alone do not ensure correct logic, and models may reach accurate conclusions through flawed processes. In this study, we introduce the MedPAIR (Medical Dataset Comparing Physicians and AI Relevance Estimation and Question Answering) dataset to evaluate how physician trainees and LLMs prioritize relevant information when answering QA questions. We obtain annotations on 1,300 QA pairs from 36 physician trainees, labeling each sentence within the question components for relevance. We compare these relevance estimates to those for LLMs, and further evaluate the impact of these "relevant" subsets on downstream task performance for both physician trainees and LLMs. We find that LLMs are frequently not aligned with the content relevance estimates of physician trainees. After filtering out physician trainee-labeled irrelevant sentences, accuracy improves for both the trainees and the LLMs. All LLM and physician trainee-labeled data are available at: http://medpair.csail.mit.edu/.
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4 questions with Rush CIO Dr. Shafiq Rab
Dr. Shafiq Rab, CIO of Rush University Medical Center in Chicago, uses his background in public health to inform his IT vision. Dr. Rab, who completed his medical degree and internal medicine residency at Karachi, Pakistan-based Dow Medical College, had his interest in public health piqued during one of his first physician jobs. While treating an urban squatters settlement in Pakistan, he worked with non-governmental organizations to address the infant mortality rate, mainly by bringing clean drinking water to its residents. "That's how I got involved in healthcare," he says. "And I remain committed to healthcare.
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Machine Translation's Past and Future
This article has been reproduced in a new format and may be missing content or contain faulty links. Contact wiredlabs@wired.com to report an issue. The outcome is a halt in federal funding for machine translation R&D. Darpa launches its Spoken Language Systems (SLS) program to develop apps for voice-activated human-machine interaction. Researchers focus on portable systems for face-to-face English-language business negotiations in German and Japanese.
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